Journal article

The Influence of Personality Disorder Symptoms on Treatment Outcomes in Bipolar Disorder: A Secondary Analysis of a Randomised Controlled Trial

Alessandra Sarmiento, Olivia M Dean, Bianca E Kavanagh, Mohammadreza Mohebbi, Michael Berk, Seetal Dodd, Sue M Cotton, Gin S Malhi, Chee H Ng, Alyna Turner

Canadian Journal of Psychiatry | Canadian Psychiatric Association | Published : 2024

Abstract

Objectives: Many people who are diagnosed with bipolar disorder also have comorbid personality disorder. Few studies have explored how personality disorder may influence pharmacological treatment outcomes. The aim of this study was to conduct a secondary analysis of data from a clinical trial of adjunctive nutraceutical treatments for bipolar depression, to determine whether maladaptive personality traits influence treatment outcomes. Methods: Scores on the Standardised Assessment of Personality – Abbreviated Scale screener were used to classify participants as having bipolar disorder with (n = 119) and without (n = 29) above threshold personality disorder symptoms (personality disorder). Ou..

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Funding Acknowledgements

The authors would like to extend their gratitude to all participants in the study. The authors would like to thank all participants of the study. The authors would also like to acknowledge the following health services involved in this study: Barwon Health, The Geelong Clinic, The Melbourne Clinic, and the University of Sydney CADE Clinic based at Royal North Shore Hospital. The authors are grateful to the Stanley Medical Research Institute, The CRC for Mental Health and the National Health and Medical Research Council for funding the study.